Evidence for the Cosmetic Skin and Hair Benefits of Cannabinoids
Dr. Gregory L. Smith, MD, NeX Therapeutics
Cannabinoids derived from hemp, known as phytocannabinoids, are a group of approximately 120 bioactive compounds found in the Cannabis sativa plant. They have gained increasing attention in recent years, emerging as promising ingredients in the cosmetics industry due to their proven therapeutic and cosmetic benefits for skin and hair. It is worth noting that they do not produce psychoactive effects associated with tetrahydrocannabinol (THC). This paper summarizes the available published in vitro, in vivo and human studies on cosmetic benefits of cannabinoids for hair and skin. Several of the mechanisms of action of cannabinoids are novel and entirely different from all other cosmetic ingredients because they interact with specific receptors in the hair and skin cells to turn “on” or “off” cellular processes. In addition, there are issues related to the formulation, legal requirements and regulatory considerations associated with incorporating cannabinoids into cosmetics formulations as discussed.
Dr. Gregory Smith earned his medical degree from Rush Medical School and his Master's of Public Health from Harvard. He is board-certified in Preventive Medicine through Walter Reed Army Medical Center. Dr. Smith has been in practice in California, Georgia and Florida for the past 30 years, initially training on the use of medical cannabis in California in 2000. Since then, he has conducted extensive research in the field of cannabinoid medications, publishing multiple textbooks including Medical Cannabis: Basic Science and Clinical Applications, Fast Facts about Medical Cannabis and Opioids through Springer press, and his most recent, "Cannabinoids", available on Amazon. Dr. Gregory Smith earned his medical degree from Rush Medical School in Chicago, and a Masters of Public Health from Harvard University. He completed residency training in Preventive Medicine at Walter Reed Army Medical Center. Since retiring from the US Army as a Major, Dr. Smith has been in practice in California, Florida, and Georgia for 30 years, initially training on the use of medical cannabis in California in 2000. Since then, he has had extensive experience and education in the field of cannabinoid medications. Dr. Smith is an avid writer, having published over a dozen peer reviewed medical publications, two medical textbooks, and a novel called "Final Review.” His book Medical Cannabis: Basic Science and Clinical Applications through Aylesbury Press, is a scientifically-based textbook directed at educating medical students and medical professionals on the science and applications of cannabinoid medications. His book on CBD for patients and caregivers is called CBD: What You Need to Know. He is also the author of THCV (tetrahydrocannabivarin) : Weight Loss, Blood Sugar and Blood Lipid Control. He contributed a chapter in the prestigious CRC Press textbook, Antioxidant Nutraceuticals – Preventive and Healthcare Applications. Most recently, he co-wrote FAST FACTS: Using Medical Cannabis for Opioid Weaning and Sparing with his brother, Dr. Kevin Smith, published through Springer press. Dr. Smith is currently Medical Advisor to Callitas Therapeutics, Sanctuary Medicinals, (US) and Green Mountain Health Alliance (Canada).
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